USA TODAY Sports’ Week 4 NFL picks: Can Patriots knock Chiefs from unbeaten ranks?

Week 4 of the NFL season has already taken a turn, the only matchup of unbeaten teams – Steelers at Titans – postponed Thursday after a fifth Tennessee player tested positive for COVID-19. 

But the NFL forges ahead, and the schedule should still provide matchups worthy of anticipation. Browns at Cowboys should be fun to watch as QBs Baker Mayfield and Dak Prescott face off for the first time in a meeting of clubs with first-year head coaches.

The Bills head to Las Vegas for the first time, looking to improve to 4-0 in the AFC East while knocking the Raiders (2-1) back down to .500.

But the game of the week will now likely take place in Arrowhead Stadium as the 2019 Super Bowl champion Kansas City Chiefs host the 2018 Super Bowl champion New England Patriots. Patrick Mahomes will share a field with Cam Newton for the first time while trying to even his record against Bill Belichick at 2-2.

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